DEA Solicitation of Information on the Use of Tryptamine-Related Compounds

[llamabox]

Expect these to all go Schedule 1 after this...
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[Federal Register: August 4, 2006 (Volume 71, Number 150)]
[Notices]
[Page 44314-44315]
From the Federal Register Online via GPO Access
[DOCID:fr04au06-97]


DEPARTMENT OF JUSTICE

Drug Enforcement Administration

[Docket No. DEA-273N]


Solicitation of Information on the Use of Tryptamine-Related
Compounds

AGENCY: Drug Enforcement Administration (DEA), Justice.

ACTION: Notice of request for information.

SUMMARY: The DEA is soliciting information on substances that are
related in chemical structure to tryptamine (see SUPPLEMENTARY
INFORMATION). The Controlled Substances Act (CSA), in Title 21 of the
United States Code (U.S.C. 812(c) Schedule I (Title 21 of the Code of
Federal Regulations (CFR 1308.11(d)), lists certain tryptamines as
Schedule I controlled substances. Some tryptamines that are not
controlled under the CSA produce central nervous system effects that
are similar to tryptamines that are controlled under the CSA.
DEA is requesting information to help determine the impact on business if
these substances were to be placed under control in the CSA.

DATES: Written comments must be postmarked, and electronic comments
must be sent, on or before October 3, 2006.

ADDRESSES: To ensure proper handling of comments, please reference
``Docket No. DEA-273N'' on all written and electronic correspondence.
Written comments being sent via regular mail should be sent to the
Deputy Assistant Administrator, Office of Diversion Control, Drug
Enforcement Administration, Washington, DC 20537, Attention: DEA
Federal Register Representative/ODL. Written comments sent via express
mail should be sent to DEA Headquarters, Attention: DEA Federal
Register Representative/ODL, 2401 Jefferson-Davis Highway, Alexandria,
VA 22301. Comments may be directly sent to DEA electronically by
sending an electronic message to XXX<!--color-->
Comments may also be sent electronically through XXX<!--color-->
using the electronic comment form provided on that
site. An electronic copy of this document is also available at the
XXX<!--color--> Web site. DEA will accept attachments to
electronic comments in Microsoft Word, WordPerfect, Adobe PDF, or Excel
file formats only. DEA will not accept any file format other than those
specifically listed here.

FOR FURTHER INFORMATION CONTACT: Christine A. Sannerud, Ph.D., Chief,
Drug and Chemical Evaluation Section, Office of Diversion Control, Drug
Enforcement Administration, Washington, DC 20537; Telephone: (202) 307-
7183.

SUPPLEMENTARY INFORMATION: Tryptamine is a compound in which the
chemical structure can be described as indole substituted at the three
position with an 2-aminoethyl chain. Although tryptamine itself is not
a controlled substance, its chemical structure constitutes the skeletal
makeup of tryptamines listed in Schedule I of the CSA, which are
classified as hallucinogenic substances.
Tryptamine is sometimes substituted on the indole ring or the 2-
aminoethyl chain or both with various substituents. Title 21 CFR
1308.11(d) lists specific substituted tryptamines in Schedule I. Also
included in Schedule I are the salts, isomers, and salts of isomers of
the listed tryptamines. The term isomer, as used in this section, means
the optical, geometric, and positional isomers.
Individuals have published detailed methods of synthesis for
substituted tryptamines and have reported pharmacological effects based
on user experiences. Law enforcement personnel encounter such
tryptamines, but because they are substituted differently than those
listed or described in the CSA, they are not subject to direct control
in Schedule I. However, some of these substances can be treated as
Schedule I controlled substance analogues if intended for human
consumption (21 U.S.C. 802(32); Sec. 813).
DEA is soliciting information on (1) The commercial uses for
tryptamines, (2) activities involving research and development, (3)
tryptamines as intermediates or analytical standards, (4) import and
domestic sources for tryptamines, and (5) any planned or anticipated
uses for tryptamines. DEA invites interested persons to provide any
information on the uses of tryptamines in industry, academia, research
and development, or other applications. Both quantitative and
qualitative information is sought.
Although information is requested for all tryptamine substances
regardless of substitutions, DEA is particularly interested in
tryptamines that meet one

[[Page 44315]]

or more of the following conditions: (a) Has a secondary or tertiary
amine formed by the substitution on the nitrogen atom of the 2-
aminoethyl chain by various alkyl groups, whether in chain or ring form
(for example, N-alkyltryptamine, N,N-dialkyltryptamine, N,N-
tetramethylenetryptamine), (b) has an alkyl substitution on the alpha
position of the 2-aminoethyl chain, and/or (c) has substituents on the
indole ring system, including, but not restricted to, various alkyl
chains, halogens, hydroxyl, alkoxy, acetyl, or alkylthio groups, at one
or more positions except the one (indole nitrogen) position. DEA is
especially interested in learning of the uses of the following
tryptamines.

2-alpha-dimethyltryptamine
4-hydroxy-N,N-diisopropyltryptamine
4-hydroxy-N,N-dipropyltryptamine
4-hydroxy-N,N-tetramethylenetryptamine
4-hydroxy-N-isopropyl-N-methyltryptamine
4-hydroxy-N-methyl-N-propyltryptamine
5,6-dimethoxy-N-isopropyl-N-methyltryptamine
5-methoxy-alpha,N-dimethyltryptamine
5-methoxy-alpha-methyltryptamine
5-methoxy-N,N-dimethyl-2-methyltryptamine
5-methoxy-N,N-dimethyltryptamine
5-methoxy-N,N-tetramethylenetryptamine
5-methoxy-N-methyltryptamine
6-methoxy-1-methyl-1,2,3,4-tetrahydro-beta-carboline
7-methoxy-1-methyl-1,2,3,4-tetrahydro-beta-carboline
9,10-didehydro-6-allyl-N,N-diethylergoline-8-beta-carboxamide
9,10-didehydro-6-propyl-N,N-diethylergoline-8-beta-carboxamide
9,10-didehydro-N,N,6-triethylergoline-8-beta-carboxamide
alpha,N-dimethyltryptamine
N,N-dibutyltryptamine
N,N-dibutyl-4-hydroxytryptamine
N,N-diethyl-2-methyltryptamine
4-hydroxy-N,N-diethyltryptamine
N,N-diethyl-5-methoxytryptamine
N,N-diisopropyl-4,5-methylenedioxytryptamine
N,N-diisopropyl-5,6-methylenedioxytryptamine
N,N-diisopropyltryptamine
N,N-dimethyl-2-methyltryptamine
N,N-dimethyl-4,5-methylenedioxytryptamine
N,N-dimethyl-4-hydroxytryptamine
N,N-dimethyl-5,6-methylenedioxytryptamine
N,N-dimethyl-5-methylthiotryptamine
N,N-dipropyltryptamine
N,N-tetramethylenetryptamine
N-butyl-N-methyltryptamine
N-ethyl-4-hydroxy-N-methyltryptamine
N-ethyl-N-isopropyltryptamine
N-ethyltryptamine
4-methoxy-N-methyl-N-isopropyltryptamine
5-methoxy-N-methyl-N-isopropyltryptamine
N-isopropyl-N-methyl-5,6-methylenedioxytryptamine
N-isopropyl-N-methyltryptamine
N-methyltryptamine
4-acetoxy-N-methyl-N-isopropyltryptamine
4-acetoxy-N,N-diisopropyltryptamine
4-acetoxy-N,N-dipropyltryptamine
4-acetoxy-N,N-diethyltryptamine
5-methoxy-N,N-diallyltryptamine
5-methoxy-N-monoallyltryptamine
5-methoxy-N-methyl-N-isopropyltryptamin
N-methyl-N-isopropyltryptamine
4-hydroxy-N,N-diethyltryptamine
5-methoxy-N,N-diethyltryptamine

Such information may be submitted to the Drug and Chemical
Evaluation Section and is requested by October 3, 2006. Information
designated as confidential or proprietary will be treated accordingly.
Confidential business information is protected from disclosure under
Exemption 4 of the Freedom of Information Act, 5 U.S.C. 552(b)(4)(FOIA)
and the Department of Justice procedures set forth in 28 CFR 16.8.

Dated: July 28, 2006.
Joseph T. Rannazzisi,
Deputy Assistant Administrator, Office of Diversion Control.
[FR Doc. E6-12599 Filed 8-3-06; 8:45 am]

BILLING CODE 4410-09-P

[boots420]

all i can say is that this is just horrible..........

[Sunshine Daydream]

I've also thought that it was a bit absurd to make a chemical endogenous to the human body (DMT) illegal. Analogue acts that apply to chemicals (both phenethylamines and tryptamines) that are endogenous to the human is illogical... Could not one make some sort of legal argument based on this to remove any regulations of the substance? I mean I'd hate to think that every person can't help but posses an illegal substance...

[Horus XCIII]

Originally Posted by Sunshine Daydream

I've also thought that it was a bit absurd to make a chemical endogenous to the human body (DMT) illegal. Analogue acts that apply to chemicals (both phenethylamines and tryptamines) that are endogenous to the human is illogical...

Everything about the drug war is illogical

Originally Posted by Sunshine Daydream

Could not one make some sort of legal argument based on this to remove any regulations of the substance? I mean I'd hate to think that every person can't help but posses an illegal substance...

They'd just reword the law "the above chemicals are not illegal when they are produced endogenously in the body" or something like that.

[llamabox]

In Japan any amount of drug is prosecutable. So anyone tested is automaticaly found with something. It just depends how small of levels they look for.

[Gamera]

This is bullshit, without question, although I am hard pressed to imagine any impact on any activity I would be interested in. First of all, any psychoactive tryptamines even if not scheduled would be illegal under the analouge act in any event and that would cover pretty much anything I could conceivably be interested in. It might impact precoursers for synthesizing obscure tryptamines, but aside from Dr. Shulgin I can't image anyone is sythesizing anything of interest that would be impacted. The psychoactive tryptamines that we all know and love have been illegal for years and all of these distant cousins are of basically no interest to any of us. I'm sure these were all on the watch list so its unlikely underground chemists were using these to cook up anything good.

Hey DEA, I got your research and development right here, fuckwads.

[Sunshine Daydream]

Originally Posted by Horus XCIII

They'd just reword the law "the above chemicals are not illegal when they are produced endogenously in the body" or something like that.

This is true. One other major part of the drug war that I find distasteful is that the government has to use loop-holes to make certain chemicals illegal... If they have to use loop-holes, it seems there was never any intention for such a law, making it against the idea of our country...

[Lefty]

Well, think of the poor meth cooks who used to be able to one stop shop @ WalMom&Popkiller. Now they have to tweek all over town getting into all kinds of shit.

[Horus XCIII]

Originally Posted by lefty

Well, think of the poor meth cooks who used to be able to one stop shop @ WalMom&Popkiller. Now they have to tweek all over town getting into all kinds of shit.

Nah, you just hop in your pickup truck, drive around the countryside, and stop at every gas station for pseudoephedrine. Just buy from different stores.

[mook]

it is something when our government has no clue on what is really important. lets spend money on the old and the homeless. lets help heroin and meth addicts. there is a million more important things than fucking with pot heads and trippers

[Sidestreet]

Maybe this is the DEA just trying to keep up with the times, stay current & therefore relevant. If Salvia became really big among our subculture, it would be scheduled pretty quick, don't you think?

[Pixie Dust]

So does that make the chemicals derivatives illegal as well? Where excactly is tryptamines isolated from anyways? (its not DMT is it?)

[Bobcat]

Originally Posted by llamabox

DEA is requesting information to help determine the impact on business if
these substances were to be placed under control in the CSA.

Lol... Only dangerous if people aren't making money on them....

Cater to the rich much, DEA?

[HepacatBioclass100]

It's like scheduling lake water. It may take a very long time for them(DEA) to read and understand TIKAL(Very Good Book). Sasha let the Genie out of the bottle. They really need a much bigger list.